Anti-Obesity Effects Of Aloe Vera – Evaluation Of Hdl-Cholesterol Protein Expression And Lipolysis

Abstract

Aim: The effect of aqueous extracts of Aloe vera on body weight, lipid accumulation in adipose tissues and HDL protein expression was evaluated in obesity induced female swiss albino mice. Experimental design: The study was conducted in four sets of mice. One set was maintained as control under normal conditions of temperature, humidity and light. Second set of mice was made obese by the administration of cholesterol rich diet for 35 days. The third set of mice was made obese by the feeding them with cholesterol rich diet for 35 days and then treated with Aloe vera extract for 15 days. The fourth set of mice was control mice administered with Aloe vera extract for 15 days. Results: Extracts of Aloe vera significantly reduced the body weight in obese mice. Also, the lipid accumulation in the adipose tissues of obese mice was found to be decreased by treatment with Aloe vera extract. Furthermore, Aloe vera elevated the HDL protein expression in the obese mice. Conclusion: These results show that Aloe vera possesses anti-obesity effects and could be used for weight loss.