Case Report on Wilson’s Disease

Abstract

Wilson's disease, also known as hepatolenticular deterioration, is a genetic  disorder in which copper is not properly eliminated but also builds up in the body organs. It possibly can be life-threatening level and affects the liver, brain, and eye. 

Clinical Findings: Titubation acute onset after trauma, fall from the back of the head, pain in the abdomen, incoordinate movement

Diagnostic Evaluation: Hb- 12.7%, total RBC-4.62 million/cu mm, total WBC- 11700/cu mm, total platelet count-1.64 lac, overall bilirubin – 14.9 mg/dl, direct bilirubin- 8.6 mg/dl, AST- 868(IU/ml), ALT- 375(IU/ml),urine test i.e., 56 μg per 24 hours, ceruloplasmin test i.e., 20 mg/dl

Visual examination: dark ring in iris (Kayser-Fleischer rings).

MRI: There is no evidence of significantly elevated T1 signal strength, although there is a slight increase in T2 signal intensity in the striatum, which is associated with neurological symptoms.

Therapeutic Intervention: Tab Neurobion forte OD, penicillamine gm OD, Tab Zn 50mg daily, Tab pyridoxine 25mg OD, Tab pacitane 2mg BD, Tab pantoprazole 40mg OD, Tab Rivotril 0.5mg BD.

Outcome: The medication has started for tremors; the wound care is given as there is a suture in the back of the head and physiotherapy is given for coordinated movements and has shown improvement in his condition.

Conclusion: The patient is admitted in AVBRH under the neuro department with continuous medical management and currently the patient's condition is stable and under observation.