Case Report on HSV ( Herpes Simplex Virus) Encephalitis


  • Ms. Shubhangi Zade, Ms. Switi Jawade, Shital Telrandhe


Herpes simplex virus 1 (HSV1) encephalitis (HSVE) is an uncommon neurological disorder caused by a viral infection of the human central nervous system (CNS).It is, nevertheless, the most prevalent cause of sporadic encephalitis. HSVE is expected to have a global yearly incidence of 1–4 cases/1,000,000. HSVE has a bimodal age distribution, with peak incidences in children under the age of three and those over the age of 50. The majority of instances affect those over the age  of 50, including men and women. The diagnosis of HSVE is complicated, and the prognosis is guarded.  If therapy is delayed or not given at all, the risk of morbidity and fatality increases. There could be medicolegal ramifications in these situations, including legal liability for medical misconduct and nervous system injury evaluation. The example of a 60year old man with HSVE is presented.

Clinical finding :- Tachycardia and tachypnoea since 4 to 5 days, fever ( high temperature) since5days, Loose stool since 3 days, vomiting since 1 to 3 days, swelling in the left to right hand since 2 days, blur vision, and unconscious since 2 days, hyper activity in the body since 4day, and fully irritability.

Diagnostic evaluation :- He is 13 year male child. All diagnostic test are done . MRI of Brain was performed using T1, T2 weighted and FLAIR sequence along with Ce-Gd study in multiple planes on sigma HD×T3 tesla MR scanner.

T1, T2 and flair:- Altered gyral signal intensity is noted right fronto- parietal lobe with edema. It is associated with thickened overlying cortex the gyri shows hyperintesnce signal on T2 wted and isointence signal on T1 wted images there is effacement. RBC, EEG, ECG, Gradient Echo:- No evidence of calcium of sequelae of haemorrhagic blood product.

Therapeutic intervention: Patient was treated  with antibiotic, analgesic, drugs to reduce pain, Antipyretic multivitamin and also provide a calcium supplements and iron supplements present case was stable but according to MRI of Brain finding.

Outcome: He had mild infection in the Brain. Patient general conditions was poor, Loss of Breathlessness.

Conclusion: This situation indicates the subsequent mental impact at the affected person, mental stress in the family members mental disorder on the society After treatment on the disease conditions the patient health improved the body.



How to Cite

Ms. Shubhangi Zade, Ms. Switi Jawade, Shital Telrandhe. (2021). Case Report on HSV ( Herpes Simplex Virus) Encephalitis. Drugs and Cell Therapies in Hematology, 10(1), 482–486. Retrieved from